Proton Radiation Therapy in Head and Neck Cancers

Sami, Muhammad; Yousuf, Muhammad; Hashmi, Qasim; Ahmad, Muneeb; Ghilman, Mohammad; Shareef, Huzaifa

doi:10.30491/IJMR.2024.471011.1292

Proton Radiation Therapy in Head and Neck Cancers

Document Type : Narrative Review

Authors

Muhammad Sami ¹

Muhammad Yousuf ¹

Qasim Hashmi ²

Muneeb Ahmad ²

Mohammad Ghilman ³

Huzaifa Shareef ³

¹ Kingston Hospital, London, United Kingdom

² Ruth K. M Pfau Civil Hospital Karachi, India

³ Dow University of Health Sciences, Civil Hospital Karachi, India

10.30491/IJMR.2024.471011.1292

Abstract

Proton therapy (PT) is one of the latest advancements in the treatment modalities of cancers. PT is specifically used to treat HnN cancer patients due to its less toxic effects on the surrounding critical structures. Keeping in view the opportunities for further advancements, there has been quite a lot of literature covering PT in HnN cancer patients. However, there has not been a compiled study that compares the toxicities, overall survival (OS), local control (LC), and quality of life (QoL) of PT with that of IMRT. The objective of this review is to compile & summarize the literature available on the toxicities, OS, LC, and QoL in HnN cancer patients post-proton therapy.

Keywords

Proton Therapy

Head and Neck Cancers

Radiation