https://www.ijmedrev.com/ International Journal of Medical Reviews en daily 1 Mon, 01 Dec 2025 00:00:00 +0330 Mon, 01 Dec 2025 00:00:00 +0330 https://www.ijmedrev.com/article_240562.html Introduction:  Digital empathy has become an essential component in modern nursing care, particularly as healthcare systems increasingly  rely  on  digital  communication  tools.  This  systematic  review  explores  the  concept,  practical  applications,  and outcomes of digital empathy in nursing practice. The goal is to understand how digital empathy contributes to patient -centered care and emotional support in virtual healthcare settings.Methods: A comprehensive literature search was conducted using databases such as PubMed, Scopus, Web of Science, SID, and  Magiran.  Keywords  included  "digital  empathy,"  "nursing  care,"  "virtual  communication,"  and  "patient -centered  care." Studies published between 2015 and 2025 were reviewed based on predefined inclusion criteria. The selected articles were analyzed to identify key themes and insights related to the implementation of digital empathy in nursing.Results:  The findings highlight that digital empathy plays a crucial role in enhancing nurse–patient interactions across virtual care  platforms.  Interventions  such  as  online  training,  digital  empathy  tools,  and  AI-supported  communication  systems  have been shown to improve emotional engagement, patient satisfaction, and trust. However, challenges like reduced non -verbal cues and digital fatigue were also noted, emphasizing the need for better training in digital communication skills and more empathy-focused system designs.Conclusion: Digital empathy has the potential to significantly improve the quality of nursing care in digital environments. While technology  can  facilitate  empathetic  communication,  maintaining  a  human -centered  approach  remains  essential.  Ongoing education and thoughtful design of digital tools that prioritize empathy are vital for delivering meaningful and compassionate care in virtual healthcare settings. https://www.ijmedrev.com/article_240564.html Scaphoid fractures are the most prevalent among carpal fractures, accounting for around 15% of acute wrist injuries. Postpone d diagnosis and treatment increases the risk of complications such as nonunion, avascular necrosis, and osteoarthritis; therefo re, swift  identification  and  management  of  these  fractures  is  critical  for  better  results.  To  ensure  an  accurate  diagnosis  and appropriate treatment, it is critical to obtain timely and appropriate confirmation or exclusion of a scaphoid fracture. Vari ous imaging  modalities  have  been  suggested  by  researchers  to  facilitate  early  and  conclusive  diagnosis  of  suspected  scaphoid fractures,  including  bone  scintigraphy,  MRI,  CT,  and  ultrasonography.  The  objective  of  this  research  is  to  conduct  a comprehensive evaluation of the research on several modalities of imaging in identifying suspected scaphoid fractures. A metaanalysis of studies published frome is the 2000s until 2023 was conducted. https://www.ijmedrev.com/article_240568.html Introduction:  Mast cells, through the repair of inflammatory mediators, cause structural and functional changes in the female reproductive  system;  however,  unregulated  mast  cell  activity  can  lead  to  fertility  problems  in  women.  On  the  other  hand, vitamin D, due to its modulatory role on mast cell function, may influence pregnancy success rates.Methods: The present study is a narrative review conducted using that incorporates observational studies (both descriptive and analytical) from the past 25 years (2000–2025).  A total of 53 articles indexed in databases such as SID, Science  Direct, Iran medex, Google Scholar, Scopus, and PubMed were reviewed.Results:  Studies  have  shown  that  vitamin  D,  by  reducing  mast  cell  activity  and  inhibiting  the  production  of  inflammatory cytokines, can help improve fertility by decreasing inflammation. Based on the available evidence, vitamin D may be consideredan  inflammatory  a  regulator  of  inflammation  in  reproductive  health.  However,  further  research  is  required  to  completely understand the precise mechanisms by which vitamin D affects mast cell activity.Conclusion:  Given  the  role  of  vitamin  D  in  enhancing  folliculogenesis,  hormonal  regulation,  and  its  anti-inflammatory  and antioxidant properties within the ovaries, existing studies suggest that vitamin D treatment may help regulate the number andactivity  of  mast  cells  in  the  endometrium  of  ovulation-induced  mice.  This  regulation  can  prevent  excessive  inflammation, improve the uterine environment for embryo implantation, and ultimately increase the success of ovulation and fertility  https://www.ijmedrev.com/article_240570.html Leukemia  remains  a  significant  clinical  challenge  despite  advances  in  chemotherapy,  targeted  therapies.  Stem  cell–based therapies  represent  a  cornerstone  in  the  treatment  of  leukemia,  offering  the  potential  for  both  curative  and  regenerative outcomes. Hematopoietic stem cell transplantation (HSCT) remains the most effective and widely used therapeutic approach, capable of restoring normal hematopoiesis following intensive chemotherapy or radiotherapy. Recent advances in stem cell biology and genetic engineering have further expanded the landscape of leukemia treatment. Induced pluripotent stem cells (iPSCs)  and  mesenchymal  stem  cells  (MSCs)  are  being  explored  for  their  roles  in  disease modeling,  drug  screening,  and  as supportive agents to enhance engraftment and reduce transplant-related complications. This review provides a comprehensive overview  of  leukemia and  its current  therapeutic approaches,  and examines  the  role of  stem  cells  in modulating  malignant hematopoiesis. Evidence from preclinical and clinical studies demonstrates that stem cells, particularly MSCs, hematopoietic stem cells (HSCs), and umbilical cord–derived or Wharton’s jelly–derived stem cells, can exert anti-leukemic effects through mechanisms  such  as  apoptosis  induction,  cell  cycle  arrest,  and  modulation  of  the  bone  marrow  microenvironment.  The therapeutic potential of stem cells is explored in the context of major leukemia subtypes, acute myeloid leukemia (AML), acut e lymphoblastic leukemia (ALL), chronic myeloid leukemia (CML), and chronic lymphocytic leukemia (CLL), highlighting both  in vitro  and  in  vivo  findings,  including  clinical  trial  evidence.  Furthermore,  emerging  therapeutic  directions  are  discussed, including the use of stem cells as drug delivery vehicles, gene therapy carriers, and sources of extracellular vesicles, alon gside strategies to disrupt leukemic stem cell niches and enhance chemotherapy efficacy. While stem cell–based interventions hold considerable  promise,  their  dualistic  effects  on  tumor  progression,  context-dependent  outcomes,  and  safety  concerns underscore the need for further mechanistic studies and carefully designed clinical trials. Collectively, this review emphasizes the evolving  role  of  stem  cell–based  therapies  in  leukemia management  and  identifies  future  directions  for  optimizing  their clinical application toward long-term disease control and improved patient outcomes. https://www.ijmedrev.com/article_240571.html Catamenial epilepsy is a hormonally influenced seizure disorder where conventional antiepileptic drugs (AEDs) often show limitedefficacy. Neurosteroids—endogenously synthesized modulators of GABAergic inhibition—represent a promising, mechanismbased  alternative.  During  hormone-sensitive  phases  of  the  menstrual  cycle,  compounds  like  ganaxolone  may  help  restore inhibitory balance and enhance seizure control. Its safety profile appears favorable, with only mild side effects. However, m ore comprehensive  studies  are  required  to confirm  its  long-term  safety and  potency  in  comparison  with  traditional  antiepileptic drugs (AEDs). https://www.ijmedrev.com/article_240574.html Diabetes  mellitus  is  a  long-term  condition  that  causes  high  blood  sugar,  with  type  2  diabetes  (T2DM)  presenting  special problems  due  to  insulin  issues.  Treatment  aims  to  manage  blood  sugar  through  lifestyle  changes  and  medications,  but  side effects  of  current  drugs  have  led  to  interest  in  new  options.  Many  patients,  especially  in  developing  countries,  use  herbal remedies like Teucrium Polium (Tp), which may help but have limited research. Some studies suggest Tp could aid in managing diabetes, though effects are unclear, and safety concerns exist, indicating a need for more research on its effects on insulin and glucose metabolism. To investigate the effectiveness of  Tp in treating diabetes mellitus, a literature search was conducted using databases such as PubMed, Science Direct, and Scopus, employing relevant keywords. We analyzed the properties and effects of  the  antidiabetic  compounds  in  Tp  utilizing  the  SwissADME  database.  This  study  aimed  to  assess  the  potential  of  Tp  for managing  diabetes.  The  compounds  examined  include  apigenin,  quercetin,  and  cirsimaritin,  each  with  molecular  weights around 300 Daltons and containing 20-23 heavy atoms, sharing similar structures but differing in properties that can assist in diabetes  treatment.  Cirsimaritin  can  easily  penetrate  biological  membranes,  making  it  effective  for  high  blood  sugar,  while apigenin is better suited for addressing low blood sugar. All three compounds are well absorbed during digestion, but rutin h as lower absorption, diminishing its effectiveness. Further research is necessary to explore their interactions and develop enha nced diabetes treatments.