Resection of Brainstem Metastases Malformation: Pearls and Pitfalls for Minimizing Complication

Arabestanino, Ali Reza; Naghibi Irvani, Sina; Dinarvand, Bita; Sabohi Moghadam, Shirin; Ai, Arman

doi:10.30491/IJMR.2022.367914.1248

Resection of Brainstem Metastases Malformation: Pearls and Pitfalls for Minimizing Complication

Document Type : Systematic Review

Authors

Ali Reza Arabestanino ¹^{, 2}^{, 3}

Sina Naghibi Irvani ⁴^{, 3}

Bita Dinarvand ⁵

Shirin Sabohi Moghadam ⁵

Arman Ai ⁶^{, 7}

¹ Harvard Medical School and Beth Israel Dissection Medical Center

² Sheikh Khalifa Medical Center

³ Shahid Beheshti University of Medical Sciences, Tehran, Iran

⁴ Harvard Medical School and Beth Israel Dissection Medical Centerl

⁵ Iran University of Medical Sciences, Tehran, Iran

⁶ Toronto Medical University

⁷ Tehran University of Medical Sciences, Tehran, Iran

10.30491/IJMR.2022.367914.1248

Abstract

Introduction: Management of brainstem metastatic tumor is challenging. brainstem metastasis is an uncommon complication of systemic cancer, generally considered to have a highly unfavorable prognosis. Surgical risks are high and standard radiation or chemotherapy have little effect. The purpose of this study is to evaluate our experience an overview of the removal of abnormalities of brain stem metastases and the general treatment protocol of these types of metastases, which are very unfavorable.
Methods: The present paper is a literature review using the following databases: PubMed, Scientific Direct, Library Genesis, using the terms: Brainstem Metastases Malformation. Articles from May 2019 were selected, resulting in a total of 19 articles that met the inclusion criteria considering their citations and respective impacts.
Results: Complications were predicted and observed according to existing factors and factors that will arise in the future. Local tumor control was achieved in 90.7% of patients.
Conclusion: The results of this small series demonstrate that treatments now can be a valuable modality for safe and effective management of brain stem metastasis. Owing to the high risk of surgical resection and low efficacy of medical treatment, radiosurgery can be proposed upfront

Keywords

Brainstem Metastatic

Radiosurgery

Systemic Cancer

Chemotherapy

Abnormalities