Catamenial epilepsy is a hormonally influenced seizure disorder where conventional antiepileptic drugs (AEDs) often show limited efficacy. Neurosteroids—endogenously synthesized modulators of GABAergic inhibition—represent a promising, mechanismbased alternative. During hormone-sensitive phases of the menstrual cycle, compounds like ganaxolone may help restore inhibitory balance and enhance seizure control. Its safety profile appears favorable, with only mild side effects. However, m ore comprehensive studies are required to confirm its long-term safety and potency in comparison with traditional antiepileptic drugs (AEDs).
Khalid,A , Asif,A , Aftab,W , Najeeb,M , Najam,A and Hannan,A . (2025). Role of Neurosteroids in Catamenial Epilepsy. International Journal of Medical Reviews, 12(4), 1040-1046. doi: 10.30491/ijmr.2025.523430.1332
MLA
Khalid,A , , Asif,A , , Aftab,W , , Najeeb,M , , Najam,A , and Hannan,A . "Role of Neurosteroids in Catamenial Epilepsy", International Journal of Medical Reviews, 12, 4, 2025, 1040-1046. doi: 10.30491/ijmr.2025.523430.1332
HARVARD
Khalid A, Asif A, Aftab W, Najeeb M, Najam A, Hannan A. (2025). 'Role of Neurosteroids in Catamenial Epilepsy', International Journal of Medical Reviews, 12(4), pp. 1040-1046. doi: 10.30491/ijmr.2025.523430.1332
CHICAGO
A Khalid, A Asif, W Aftab, M Najeeb, A Najam and A Hannan, "Role of Neurosteroids in Catamenial Epilepsy," International Journal of Medical Reviews, 12 4 (2025): 1040-1046, doi: 10.30491/ijmr.2025.523430.1332
VANCOUVER
Khalid A, Asif A, Aftab W, Najeeb M, Najam A, Hannan A. Role of Neurosteroids in Catamenial Epilepsy. Int J Med Rev. 2025;12(4):1040-1046. doi: 10.30491/ijmr.2025.523430.1332
